LIANYUNGANG JUDE PHARMACEUTICAL CHEMICAL CO.,LTD.
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China (Mainland)
Business Type:Trading Company
Tel: 86-518-18168156570
Mobile: 0086-18168156570
Tel: 86-518-18168156570
Fax: 0518-85193109
URL: http://www.judepharmachem.com/
Province/state: jiangsu
City: lianyungang
Street: NO.8 LINGZHOU EAST ROAD,HI-TECH ZONE,LIANYUNGANG CITY,JIANGSU PROVINCE,CHINA
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CAS NO.25086-89-9
1. Rich experience
We specialize in this filed for more than 20 years, our chemical products exported to all over the world and and we established long friendly relations of cooperation with our clients.
2. Great quality,purity and favorable
Good quality is one of our biggest secrets to success; You can get the best product quality you demand and best service from us.
3. Safest and fastest delivery
We have adequate stock so that we can deliver the products by air as soon as receiving the payment. And fast and discreet shipment will be arranged to pass customs.
4. Great after-sales service
Any needs or questions contact me freely.
We will supply accurate and timely information.
About product quality, product application scope, package, commodity market price and trend, transportation situation and so on.
Product Detail
Product Name:Copvodione
Chemical Description:Vinylpyrrolidone with Vinyl Acetate Copolymer,PVP/VA 64 Powder
INCI/CTFA:VP/VA Copolymer
Pharmacopeia Name:Copovidone(Copovidonum)
CAS NO.:25086-89-9
Formula structure:
Properties: White or creamy white,free-flowing power with characteristic smell,hygroscopic.Good solubility in water,alcohol and other organic solvents.
Applications:In view of it’s excellent adhesiveness ,film hard and other properties,Copovidone mainly used as water-soluble binder and dry binder in wet/direct granulation processes,also it can be used as film forming materials.
Specifications:
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Appearance |
White to creamy white,free-flowing powder |
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K Value(Labled K value at 30) |
27-32.4 |
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Aldehyde |
500 ppm max. |
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Peroxide |
400 ppm max. |
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Hydrazine |
1 ppm max. |
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Monomers(Residue VP+Residue VA) |
0.1% max. |
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Impurity A(2-Pyrrolidone) |
0.5% max. |
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Heavy Metals |
20 ppm max. |
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Moisture |
5.0% max. |
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Sulphated Ash |
0.1% max. |
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VA content |
35.3-42% max. |
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Nitrogen |
7.0-8.0 % |
Poly(1-vinylpyrrolidone-co-vinyl acetate), also known as Copovidone, is a water-soluble polymer with a 1:2.4 mole ratio of vinylpyrrolidone (VP) to vinyl acetate (VA). It is a white to yellowish-white amorphous powder, typically spray-dried with a relatively fine particle size. Copovidone has a slight odor and a faint taste.
Used in Pharmaceutical Applications:
Poly(1-vinylpyrrolidone-co-vinyl acetate) is used as a pharmaceutical excipient for improving the uptake and drug loading of various pharmaceutical agents, including contraceptive patches. It enhances the bioavailability and efficacy of the drugs by increasing their solubility and stability in the formulation.
Used in Drug Delivery Systems:
In the drug delivery industry, Poly(1-vinylpyrrolidone-co-vinyl acetate) is utilized as a carrier material for the development of novel drug delivery systems. These systems aim to improve the targeted delivery, bioavailability, and therapeutic outcomes of various pharmaceutical agents by providing a controlled and sustained release of the drug.
Used in Cosmetic Applications:
Poly(1-vinylpyrrolidone-co-vinyl acetate) is also used in the cosmetic industry as a film-forming agent, providing a smooth and uniform texture to the products. It helps improve the skin's appearance and feel by forming a protective layer on the skin's surface, which can also enhance the stability and shelf life of cosmetic formulations.
Used in Adhesive Applications:
In the adhesive industry, Poly(1-vinylpyrrolidone-co-vinyl acetate) is employed as a component in the formulation of pressure-sensitive adhesives. It contributes to the adhesive's tackiness, shear strength, and peel resistance, making it suitable for various applications such as packaging, labeling, and medical tapes.
Used in Textile Applications:
Poly(1-vinylpyrrolidone-co-vinyl acetate) is utilized in the textile industry as a binder and sizing agent for fibers. It helps improve the adhesion and bonding of fibers, enhancing the strength and durability of the textile products. Additionally, it can be used to provide a protective coating on fibers, offering resistance to abrasion, moisture, and other environmental factors.
Copovidone is manufactured by free-radical polymerization of vinylpyrrolidone and vinyl acetate in a ratio of 6 : 4. The synthesis is conducted in an organic solvent owing to the insolubility of vinyl acetate in water.
Copovidone is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations. In tableting, copovidone can be used as a binder for direct compression and as a binder in wet granulation. Copovidone is often added to coating solutions as a film-forming agent. It provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.
Moderately toxic by ingestion.Combustible, especially in powdered form. Incompatiblewith strong oxidising agents, strong reducing agents. Whenheated to decomposition it emits toxic vapors of NOx.
Copovidone is used widely in pharmaceutical formulations and is generally regarded as nontoxic. However, it is moderately toxic by ingestion, producing gastric disturbances. It has no irritating or sensitizing effects on the skin. A study was conducted to look at the carcinogenicity and chronic toxicity of copovidone (Kollidon VA 64) in Wistar rats and Beagle dogs. The results of these studies demonstrated the absence of any significant toxicological findings of high dietary levels of copodivone in rats and dogs, resulting in noobserved- adverse-effect levels of 2800 mg/kg body-weight/day in rats and 2500 mg/kg body-weight/day in dogs, the highest doses tested. LD50 (rat, oral): >0.63 g/kg
Copovidone is stable and should be stored in a well-closed container in a cool, dry place.
Copovidone is compatible with most organic and inorganic pharmaceutical ingredients. When exposed to high water levels, copovidone may form molecular adducts with some materials; see Crospovidone and Povidone.
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By Courier |
By Air |
By Sea |
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≤50kg |
50kg-500kg |
≥500kgs |
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3-7 Days |
5-7 Days |
15-20 Days |
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Door to Door |
Airport to Airport |
Seaport to Seaport |
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Easy to get products |
Need do custom clearance |
Need do custom clearance |
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Payment Terms: |
T/T, L/C |
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Delivery time: |
1-3 working days after confirming the payment |
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Delivery: |
Door to Door,safety grantee 4 big express: DHL, TNT, FedEx, UPS Bulk quantity by Sea |
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Packaging Details: |
Plastic bag & kraft paper bag & fiber drum & metal bucket 1kg /25kg/200kg/1000kg per bag/drum |
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Supply Ability: |
Bulk quantity in stock |
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LIANYUNGANG JUDE PHARMACEUTICAL CHEMICAL CO.,LTD. IS AN ACTIVE AND RELIABLE WORLDWIDE INGREDIENTS SUPPLIER, MAINLY FOCUS ON API, PHARMACEUTICAL EXCIPIENTS,FOOD INGREDIENTS,DISINFECTION AND CLEAN CHEMICALS.WE ARE PROMOTING QUALIFIED PRODUCTS TO WORLDWIDE CLIENTS UNDER GMP, HACCP, KOSHER, ISO, HALAL AND OTHER CERTIFIED PROCESS CONTROL SYSTEMS.
WITH MORE THAN 20 YEARS PROFESSIONAL EXPERIENCES IN SOURCING AND MARKETING.WE WILL PROVIDE CUSTOMERS WITH ALL-ROUND SERVICE AND SUPPORT FROM TECHNOLOGY, PRODUCTION, MARKETING, SALES, LOGISTICS, AFTER-SALES AND OTHER ASPECTS. WITH SOLID PROFESSIONAL KNOWLEDGE, WE WILL CREATE HEALTHY AND SUSTAINABLE DEVELOPMENT AND VALUE FOR OUR CUSTOMERS.
LOOK FORWARD TO THE OPPORTUNITY TO WORK WITH YOU AS A PARTNER.
Q1: What is your MOQ
A:Our MOQ is 25kg for your evaluation quality of our goods on the condition that sample charge is 100% paid.
Q2: Is there any discount
A:Yes, for larger quantity, we always support with better price.
Q3: What payment terms do you accept
A:We'd like to accept T/T, L/C, Paypal, or .
Q4: How long will it take to get the goods
A:We can delivery small order via DHL, UPS, TNT, FEDEX, EMS.within 3days.And 7to14days to load on port by sea.
Q5: How do you treat quality complaint
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6: How can we trust you
A: You are always warmly welcomed to visit us at any time. Lookchem has audited our company and approved our credit.
Q7: Do you test all your goods before delivery
A: Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.